Cribier et al. [19] conducted a diagnostic trial in France among patients & HCs (n= 86) buy modafinil online hong kong on relation vascularity and inflammation. The study revealed that vasculature and inflammatory responses are interrelated and aiding in pathology of rosacea. The result of excess of blood supply leads to hyper-erythema..
As a minimally invasive surgery PCNL has been widely accepted. Several new techniques of PCNL, such as mini-PCNL and tubeless PCNL, have been reported to decrease the morbidity and analgesic requirement, but even then it is still a painful procedure. Tangpaitoon and colleagues [18] had reported that analog pain score (VAS scores) at the postoperative 1 hour and 4 hour were 68.8 ± 12.7 mm and 50.7 ± 25.8 mm, respectively, for patients who underwent PCNL with general anesthesia. Singh et al. [19] had reported that VAS on the first postoperative day morning was 65.6 ± 14.4 mm in the general anesthesia patients. Thus, it is clear that the postoperative administration of analgesic agents is necessary in patients undergoing PCNL..
is infertility, the first line would be ART. tolerance and withdrawal (Gelder M et . • Relative simplicity of examination buy modafinil online hong kong which does not require. centrifugation can be used to remove food debris, leaving bacterial centrifugation can be used to remove food debris, leaving bacterial. Cyclooxygenases (COX), components of the arachidonic acid cascade are a family of catalyzing enzymes that convert cellular arachidonic acid to prostaglandin. There are two major cyclooxygenases, COX-1 and COX-21. COX-1 is a housekeeping gene that is expressed constitutively in a variety of human tissues. COX-2 is an inducible gene2. Recently it has been reported that COX-2 is overexpressed in many human tumors, including colorectal carcinoma, gastric carcinoma, gallbladder carcinoma and liver cancer3-6. This observation has suggested that COX-2 may play a critical role in the carcinogenesis and progression of tumors. Many researchs have demonstrated that COX-2 is not only responsible for cell proliferation and transformation, but also for inducing angiogenesis7,8. However, the mechanism is unclear.. during sex buy modafinil online hong kong vulvar symptoms,. Our findings suggest that down-regulation PML(NLS-) expression can inhibit the proliferation of HL-60 cells and induce their apoptosis. PML(NLS-) is a putative tumor promoter factor in human leukemia cells. PML(NLS-) over-expression can promote the growth and induce the apoptosis. PML(NLS-) may become a potential target in the therapy of leukemia. Further investigations may be helpful to develop novel therapeutic approaches for leukemia.. Our observations are in line with previous reports that low albumin is of prognostic value on mortality in HF patients.61 buy modafinil online hong kong 62, 65, 66, 69, 137, 226-228 Our data are also concordant with clinical observations that demonstrate that serum GGT, a robust predictor of mortality due to CVD in younger individuals, did not predict mortality in individuals aged 70 years or more.69 The prognostic value of GGT and/or adiponectin in HF patients has not been reported previously. Of note, in contrast to the present multivariate analyses, most of the previous prognostic studies in patients with HF examined only few liver parameters (mainly albumin) and often did not control for possible confounders, clinical and laboratory.67. We demonstrate for the first time a possible role for prolactin in ASST-positive CU patients and its association with disease severity. We recommend larger prospective studies to assess changes in prolactin and DHEA-S levels after complete disease remission.. The rats were palpated once a week to record the presence and. Rigid bronchoscopy is very effective procedure for inhaled foreign body removal with fewer complications. Proper use of diagnostic techniques provides a high degree of success buy modafinil online hong kong and the treatment modality to be used depending on the type of the foreign body is mostly satisfactory.. that results in class label and regression mode that gives value. When that results in class label and regression mode that gives value. When. This study included 65 premenarchal patients who underwent surgery due to adnexal masses at our hospital between January 1990 and March 2012. Clinicopathological data was retrospectively collected from the patients' hospital medical records. The records were analyzed in terms of demographic characteristics buy modafinil online hong kong initial symptoms, complications, surgical methods and histological diagnoses. The study was approved by the Institutional Review Board (KC12RISI0881). All statistical analyses were performed using Student's t test and the Fischer exact test. A p value of <0.05 was considered statistically significant.. the ability of transcriptional inhibition. dCas9-VP16 or dCas9-VP64.
However, while there are numerous studies showing that the visual. 2012 there was one fertility/subfertility problem managed for 652. daily. The patient should complete a. The data were analyzed using the t-test and Spearman correlation test. The circulating NPM mut.A levels were summarized as medium and quartile M (P25 buy modafinil online hong kong P75). SPSS (Version 16.0) was used for statistical analysis. A value of p<0.05 was considered statistically significant. All clinical data were collected from patient records and organized in the leukemia clinical database.. Resistance to methicillin was detected with a cefoxitin disk diffusion assay and confirmed with a MRSA-agar and MRSA detection kit. Antimicrobial susceptibility testing was performed by a disk diffusion assay and interpreted according to the 2012 guidelines of the Antibiogram Committee of the French Society for Microbiology. Decreased susceptibility to glycopeptides was confirmed using the population analysis profile-area under the curve (PAP-AUC) method. The presence of the mecA gene was detected by polymerase chain reaction. Bacterial DNA was extracted according to the manufacturer's recommended protocol using commercial extraction kits. Strains were extensively characterized using the DNA microarray. Resistance to methicillin was detected with a cefoxitin disk diffusion assay and confirmed with a MRSA-agar and MRSA detection kit. Antimicrobial susceptibility testing was performed by a disk diffusion assay and interpreted according to the 2012 guidelines of the Antibiogram Committee of the French Society for Microbiology. Decreased susceptibility to glycopeptides was confirmed using the population analysis profile-area under the curve (PAP-AUC) method. The presence of the mecA gene was detected by polymerase chain reaction. Bacterial DNA was extracted according to the manufacturer's recommended protocol using commercial extraction kits. Strains were extensively characterized using the DNA microarray.. Alcohol misuse is important because more than 76 million people in the world have alcohol use disorders [ 1 ]. In Western countries, 10% of the general population older than 14 years are affected by alcohol abuse or dependence [ 2 , 3 ]. The lifetime risk of alcohol use disorders for men is greater than 20% [ 4 ]. Excessive alcohol consumption (EAC) is related to more than 60 different disorders and causes worldwide 1.8 million deaths a year (3.2% of total) [ 5 , 6 ]. In Switzerland, 5.2% of deaths in men and 1.4% deaths in women are related to EAC as well as 3% of all deaths in England [ 7 , 8 ]. Excessive alcohol consumption is the leading cause (50%) of nonischemic dilated cardiomyopathy in industrialized countries [ 3 ]. Alcohol misuse is important because more than 76 million people in the world have alcohol use disorders [ 1 ]. In Western countries, 10% of the general population older than 14 years are affected by alcohol abuse or dependence [ 2 , 3 ]. The lifetime risk of alcohol use disorders for men is greater than 20% [ 4 ]. Excessive alcohol consumption (EAC) is related to more than 60 different disorders and causes worldwide 1.8 million deaths a year (3.2% of total) [ 5 , 6 ]. In Switzerland, 5.2% of deaths in men and 1.4% deaths in women are related to EAC as well as 3% of all deaths in England [ 7 , 8 ]. Excessive alcohol consumption is the leading cause (50%) of nonischemic dilated cardiomyopathy in industrialized countries [ 3 ].. The presence of a BCG scar was not significantly associated with reduced risk for an individual to be categorized as intermediate or atopic (intermediate vs. non-atopy: adjusted odds ratio (aOR) 0.83; 95% CI 0.26 buy modafinil online hong kong 2.60; p = 0.75, atopy vs. non-atopy: aOR 0.89; 95% CI 0.33, 2.37; p = 0.81, respectively). The statistical power was calculated as 45.3%. We observed that older patients had a lower risk of developing atopy (intermediate vs. non-atopy: aOR for every one year of age 0.97; 95% CI 0.94, 1.00; p = 0.05, atopy vs. non-atopy: aOR for every one year of age 0.91; 95% CI 0.89, 0.94; p < 0.01, respectively). The mean diameter of BCG scar was not associated with risk of atopy, after adjusting for age and sex (Table 2).. The genotypic distributions of ICAM-1 SNPs in the subjects with CAD and without CAD are summarized in Table 3. The genotypic frequency of ICAM-1 SNP rs281432 met the Hardy-Weinberg equilibrium (p>0.05 buy modafinil online hong kong χ2 value: 1.47; df: 2). The frequencies of ICAM-1 SNPs rs3093030, rs5491 and rs5498 were also in Hardy-Weinberg equilibrium (p>0.05, χ2 value: 0.00029; p>0.05, χ2 value: 0.53 and p>0.05, χ2 value: 0.97, respectively).. instances where the same serovar was recovered from a pond for more instances where the same serovar was recovered from a pond for more. In conclusion, the present study provides in vitro evidence to support the previous clinical observations that reported lower incidence and less aggressive nature of prostate cancer in those who regularly consumed tomato based products. Our study also suggests concentrations at which biological effects of lycopene are likely to occur and are therefore relevant for further investigation into the clinical efficacy of this nutrient. Further studies are underway in our laboratory to examine the molecular pathways through which lycopene is likely to influence the invasive properties of cancer cells.. know that mammals developed this cognitive capacity as they evolved. Our results have shown that smoking contributes to increase in the GGT activity in AP patients with the TC genotypes for both SNPs (rs5751901 and rs2236626). It could reflect elevated metabolism of smoke xenobiotics via the above-mentioned mechanism, and confirm its toxic effect on cells. In the smokers with the TC genotypes, increase in the GGT activity could be a result of slightly increased GGT concentration. SNPs can make changes in amino acids encoding, which may have an effect on promoter activity, gene expression and stability of mRNA or its subcellular localization, influencing GGT concentration [31]. SNPs can be also related to up-regulation GGT mRNA at transcription level under oxidative stress conditions. There is evidence that the GGT gene expression in animals and humans is controlled by redox mechanisms and signal pathways activated in response to oxidative stress [15,32,33]. Zhang et al. [33] described that this pathway includes, among others, activation of protein kinase C, mitogen-activated protein kinase and activation of protein 1-binding element which are also induced by smoke xenobiotics [34]. The correlations between GGT and oxidative stress markers showed in the groups of smokers could support this thesis. It can indicate the role of GGT as a marker of oxidative stress induced by tobacco smoke xenobiotics. In the AP patients with the TC genotypes for both tested SNPs it was also observed that recurrent course of AP occurred only in smokers (data not shown). This group of AP patients showed the weakest tendency to normalize the GGT activity during hospitalization. Additionally, tobacco smoking in the subjects with the TC genotypes for SNP rs5751901 elevated the risk of AP occurrence by more than three times. It can be associated with pro-inflammatory effect of smoke xenobiotics via free radicals pathway, which was reported in other papers [34,35].. On the other hand, all 4 strains of C. albicans increased rapidly, reaching the maximum concentration within 48 hours (Figure 1d). There were significant increases in the mean values of the 4 strains both at 24hours (p<0.05) and at 48 hours (p<0.01).. (Oxoid code CM1082, Basingstoke, UK). A 10 ml overlay of molten. into the FMIA.. Statistically significant improvement of hemorheological parameters upon the introduction of oncotic therapy was recorded in the values of Htc buy modafinil online hong kong fibrinogen and diastolic blood pressure, whereas other parameters (uric acid, platelet count, uterine arterial RI on the side of placentation, and systolic blood pressure) showed a decrease that did not reach statistical significance. Upon the introduction of oncotic therapy, favorable changes in perinatal Doppler ultrasonography parameters were recorded in uterine arterial RI but not in middle cerebral artery RI. There was no statistically significant change in the fetal biophysical profile (FBP) values either. Perinatal outcome was favorable with a mean 5-min Apgar score 8 and pH 7.26. Lower birth weight values (mean 2631 ± 407 g) were consequential to preterm delivery and IUGR, resulting in a number of neonates requiring NICU treatment..
that need the most social assistance are frequently unable to ‘plug-in’. to complexity in communication. This process is slow and because the. The present study was single centered. Therefore, it cannot reflect the whole condition of the Iranian society. In spite of this limitation, due to the fact that the Iran National Tumor Bank, Cancer Biology Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran contained the samples of patients from different provinces, it can reflect the present status. Expressing the general condition of Iran, multicentral studies are necessary. In the present study, the sex and age status of patients on the histopathological profile of cancer were not investigated. The impact of age and sex on the extent of malignancy is suggested in future studies. The present study was single centered. Therefore, it cannot reflect the whole condition of the Iranian society. In spite of this limitation, due to the fact that the Iran National Tumor Bank, Cancer Biology Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran contained the samples of patients from different provinces, it can reflect the present status. Expressing the general condition of Iran, multicentral studies are necessary. In the present study, the sex and age status of patients on the histopathological profile of cancer were not investigated. The impact of age and sex on the extent of malignancy is suggested in future studies..
As a minimally invasive surgery PCNL has been widely accepted. Several new techniques of PCNL, such as mini-PCNL and tubeless PCNL, have been reported to decrease the morbidity and analgesic requirement, but even then it is still a painful procedure. Tangpaitoon and colleagues [18] had reported that analog pain score (VAS scores) at the postoperative 1 hour and 4 hour were 68.8 ± 12.7 mm and 50.7 ± 25.8 mm, respectively, for patients who underwent PCNL with general anesthesia. Singh et al. [19] had reported that VAS on the first postoperative day morning was 65.6 ± 14.4 mm in the general anesthesia patients. Thus, it is clear that the postoperative administration of analgesic agents is necessary in patients undergoing PCNL..
is infertility, the first line would be ART. tolerance and withdrawal (Gelder M et . • Relative simplicity of examination buy modafinil online hong kong which does not require. centrifugation can be used to remove food debris, leaving bacterial centrifugation can be used to remove food debris, leaving bacterial. Cyclooxygenases (COX), components of the arachidonic acid cascade are a family of catalyzing enzymes that convert cellular arachidonic acid to prostaglandin. There are two major cyclooxygenases, COX-1 and COX-21. COX-1 is a housekeeping gene that is expressed constitutively in a variety of human tissues. COX-2 is an inducible gene2. Recently it has been reported that COX-2 is overexpressed in many human tumors, including colorectal carcinoma, gastric carcinoma, gallbladder carcinoma and liver cancer3-6. This observation has suggested that COX-2 may play a critical role in the carcinogenesis and progression of tumors. Many researchs have demonstrated that COX-2 is not only responsible for cell proliferation and transformation, but also for inducing angiogenesis7,8. However, the mechanism is unclear.. during sex buy modafinil online hong kong vulvar symptoms,. Our findings suggest that down-regulation PML(NLS-) expression can inhibit the proliferation of HL-60 cells and induce their apoptosis. PML(NLS-) is a putative tumor promoter factor in human leukemia cells. PML(NLS-) over-expression can promote the growth and induce the apoptosis. PML(NLS-) may become a potential target in the therapy of leukemia. Further investigations may be helpful to develop novel therapeutic approaches for leukemia.. Our observations are in line with previous reports that low albumin is of prognostic value on mortality in HF patients.61 buy modafinil online hong kong 62, 65, 66, 69, 137, 226-228 Our data are also concordant with clinical observations that demonstrate that serum GGT, a robust predictor of mortality due to CVD in younger individuals, did not predict mortality in individuals aged 70 years or more.69 The prognostic value of GGT and/or adiponectin in HF patients has not been reported previously. Of note, in contrast to the present multivariate analyses, most of the previous prognostic studies in patients with HF examined only few liver parameters (mainly albumin) and often did not control for possible confounders, clinical and laboratory.67. We demonstrate for the first time a possible role for prolactin in ASST-positive CU patients and its association with disease severity. We recommend larger prospective studies to assess changes in prolactin and DHEA-S levels after complete disease remission.. The rats were palpated once a week to record the presence and. Rigid bronchoscopy is very effective procedure for inhaled foreign body removal with fewer complications. Proper use of diagnostic techniques provides a high degree of success buy modafinil online hong kong and the treatment modality to be used depending on the type of the foreign body is mostly satisfactory.. that results in class label and regression mode that gives value. When that results in class label and regression mode that gives value. When. This study included 65 premenarchal patients who underwent surgery due to adnexal masses at our hospital between January 1990 and March 2012. Clinicopathological data was retrospectively collected from the patients' hospital medical records. The records were analyzed in terms of demographic characteristics buy modafinil online hong kong initial symptoms, complications, surgical methods and histological diagnoses. The study was approved by the Institutional Review Board (KC12RISI0881). All statistical analyses were performed using Student's t test and the Fischer exact test. A p value of <0.05 was considered statistically significant.. the ability of transcriptional inhibition. dCas9-VP16 or dCas9-VP64.
However, while there are numerous studies showing that the visual. 2012 there was one fertility/subfertility problem managed for 652. daily. The patient should complete a. The data were analyzed using the t-test and Spearman correlation test. The circulating NPM mut.A levels were summarized as medium and quartile M (P25 buy modafinil online hong kong P75). SPSS (Version 16.0) was used for statistical analysis. A value of p<0.05 was considered statistically significant. All clinical data were collected from patient records and organized in the leukemia clinical database.. Resistance to methicillin was detected with a cefoxitin disk diffusion assay and confirmed with a MRSA-agar and MRSA detection kit. Antimicrobial susceptibility testing was performed by a disk diffusion assay and interpreted according to the 2012 guidelines of the Antibiogram Committee of the French Society for Microbiology. Decreased susceptibility to glycopeptides was confirmed using the population analysis profile-area under the curve (PAP-AUC) method. The presence of the mecA gene was detected by polymerase chain reaction. Bacterial DNA was extracted according to the manufacturer's recommended protocol using commercial extraction kits. Strains were extensively characterized using the DNA microarray. Resistance to methicillin was detected with a cefoxitin disk diffusion assay and confirmed with a MRSA-agar and MRSA detection kit. Antimicrobial susceptibility testing was performed by a disk diffusion assay and interpreted according to the 2012 guidelines of the Antibiogram Committee of the French Society for Microbiology. Decreased susceptibility to glycopeptides was confirmed using the population analysis profile-area under the curve (PAP-AUC) method. The presence of the mecA gene was detected by polymerase chain reaction. Bacterial DNA was extracted according to the manufacturer's recommended protocol using commercial extraction kits. Strains were extensively characterized using the DNA microarray.. Alcohol misuse is important because more than 76 million people in the world have alcohol use disorders [ 1 ]. In Western countries, 10% of the general population older than 14 years are affected by alcohol abuse or dependence [ 2 , 3 ]. The lifetime risk of alcohol use disorders for men is greater than 20% [ 4 ]. Excessive alcohol consumption (EAC) is related to more than 60 different disorders and causes worldwide 1.8 million deaths a year (3.2% of total) [ 5 , 6 ]. In Switzerland, 5.2% of deaths in men and 1.4% deaths in women are related to EAC as well as 3% of all deaths in England [ 7 , 8 ]. Excessive alcohol consumption is the leading cause (50%) of nonischemic dilated cardiomyopathy in industrialized countries [ 3 ]. Alcohol misuse is important because more than 76 million people in the world have alcohol use disorders [ 1 ]. In Western countries, 10% of the general population older than 14 years are affected by alcohol abuse or dependence [ 2 , 3 ]. The lifetime risk of alcohol use disorders for men is greater than 20% [ 4 ]. Excessive alcohol consumption (EAC) is related to more than 60 different disorders and causes worldwide 1.8 million deaths a year (3.2% of total) [ 5 , 6 ]. In Switzerland, 5.2% of deaths in men and 1.4% deaths in women are related to EAC as well as 3% of all deaths in England [ 7 , 8 ]. Excessive alcohol consumption is the leading cause (50%) of nonischemic dilated cardiomyopathy in industrialized countries [ 3 ].. The presence of a BCG scar was not significantly associated with reduced risk for an individual to be categorized as intermediate or atopic (intermediate vs. non-atopy: adjusted odds ratio (aOR) 0.83; 95% CI 0.26 buy modafinil online hong kong 2.60; p = 0.75, atopy vs. non-atopy: aOR 0.89; 95% CI 0.33, 2.37; p = 0.81, respectively). The statistical power was calculated as 45.3%. We observed that older patients had a lower risk of developing atopy (intermediate vs. non-atopy: aOR for every one year of age 0.97; 95% CI 0.94, 1.00; p = 0.05, atopy vs. non-atopy: aOR for every one year of age 0.91; 95% CI 0.89, 0.94; p < 0.01, respectively). The mean diameter of BCG scar was not associated with risk of atopy, after adjusting for age and sex (Table 2).. The genotypic distributions of ICAM-1 SNPs in the subjects with CAD and without CAD are summarized in Table 3. The genotypic frequency of ICAM-1 SNP rs281432 met the Hardy-Weinberg equilibrium (p>0.05 buy modafinil online hong kong χ2 value: 1.47; df: 2). The frequencies of ICAM-1 SNPs rs3093030, rs5491 and rs5498 were also in Hardy-Weinberg equilibrium (p>0.05, χ2 value: 0.00029; p>0.05, χ2 value: 0.53 and p>0.05, χ2 value: 0.97, respectively).. instances where the same serovar was recovered from a pond for more instances where the same serovar was recovered from a pond for more. In conclusion, the present study provides in vitro evidence to support the previous clinical observations that reported lower incidence and less aggressive nature of prostate cancer in those who regularly consumed tomato based products. Our study also suggests concentrations at which biological effects of lycopene are likely to occur and are therefore relevant for further investigation into the clinical efficacy of this nutrient. Further studies are underway in our laboratory to examine the molecular pathways through which lycopene is likely to influence the invasive properties of cancer cells.. know that mammals developed this cognitive capacity as they evolved. Our results have shown that smoking contributes to increase in the GGT activity in AP patients with the TC genotypes for both SNPs (rs5751901 and rs2236626). It could reflect elevated metabolism of smoke xenobiotics via the above-mentioned mechanism, and confirm its toxic effect on cells. In the smokers with the TC genotypes, increase in the GGT activity could be a result of slightly increased GGT concentration. SNPs can make changes in amino acids encoding, which may have an effect on promoter activity, gene expression and stability of mRNA or its subcellular localization, influencing GGT concentration [31]. SNPs can be also related to up-regulation GGT mRNA at transcription level under oxidative stress conditions. There is evidence that the GGT gene expression in animals and humans is controlled by redox mechanisms and signal pathways activated in response to oxidative stress [15,32,33]. Zhang et al. [33] described that this pathway includes, among others, activation of protein kinase C, mitogen-activated protein kinase and activation of protein 1-binding element which are also induced by smoke xenobiotics [34]. The correlations between GGT and oxidative stress markers showed in the groups of smokers could support this thesis. It can indicate the role of GGT as a marker of oxidative stress induced by tobacco smoke xenobiotics. In the AP patients with the TC genotypes for both tested SNPs it was also observed that recurrent course of AP occurred only in smokers (data not shown). This group of AP patients showed the weakest tendency to normalize the GGT activity during hospitalization. Additionally, tobacco smoking in the subjects with the TC genotypes for SNP rs5751901 elevated the risk of AP occurrence by more than three times. It can be associated with pro-inflammatory effect of smoke xenobiotics via free radicals pathway, which was reported in other papers [34,35].. On the other hand, all 4 strains of C. albicans increased rapidly, reaching the maximum concentration within 48 hours (Figure 1d). There were significant increases in the mean values of the 4 strains both at 24hours (p<0.05) and at 48 hours (p<0.01).. (Oxoid code CM1082, Basingstoke, UK). A 10 ml overlay of molten. into the FMIA.. Statistically significant improvement of hemorheological parameters upon the introduction of oncotic therapy was recorded in the values of Htc buy modafinil online hong kong fibrinogen and diastolic blood pressure, whereas other parameters (uric acid, platelet count, uterine arterial RI on the side of placentation, and systolic blood pressure) showed a decrease that did not reach statistical significance. Upon the introduction of oncotic therapy, favorable changes in perinatal Doppler ultrasonography parameters were recorded in uterine arterial RI but not in middle cerebral artery RI. There was no statistically significant change in the fetal biophysical profile (FBP) values either. Perinatal outcome was favorable with a mean 5-min Apgar score 8 and pH 7.26. Lower birth weight values (mean 2631 ± 407 g) were consequential to preterm delivery and IUGR, resulting in a number of neonates requiring NICU treatment..
that need the most social assistance are frequently unable to ‘plug-in’. to complexity in communication. This process is slow and because the. The present study was single centered. Therefore, it cannot reflect the whole condition of the Iranian society. In spite of this limitation, due to the fact that the Iran National Tumor Bank, Cancer Biology Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran contained the samples of patients from different provinces, it can reflect the present status. Expressing the general condition of Iran, multicentral studies are necessary. In the present study, the sex and age status of patients on the histopathological profile of cancer were not investigated. The impact of age and sex on the extent of malignancy is suggested in future studies. The present study was single centered. Therefore, it cannot reflect the whole condition of the Iranian society. In spite of this limitation, due to the fact that the Iran National Tumor Bank, Cancer Biology Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran contained the samples of patients from different provinces, it can reflect the present status. Expressing the general condition of Iran, multicentral studies are necessary. In the present study, the sex and age status of patients on the histopathological profile of cancer were not investigated. The impact of age and sex on the extent of malignancy is suggested in future studies..
